human RDH12 Over-expression AAV

Cat. No: AAV-220964

Availability: 3-5 weeks

Name: AAV-h-RDH12

This is an AAV expressing Human RDH12.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RDH12
Gene Name: retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Gene ID: 145226
Gene Synonyms: LCA13; RP53; SDR7C2
ORF Size: 951 bp
RefSeq#: BC025724
Gene Description: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
UniGene ID: Hs.415322
HGNC ID: HGNC:19977