human PVRL3 Over-expression AAV

Cat. No: AAV-220420

Availability: 3-5 weeks

Name: AAV-h-PVRL3

This is an AAV expressing Human NECTIN3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NECTIN3
Gene Name: nectin cell adhesion molecule 3
Gene ID: 25945
Gene Synonyms: CD113; CDW113; NECTIN-3; PPR3; PRR3; PVRL3; PVRR3
ORF Size: 1101 bp
RefSeq#: BC067808
Gene Description: PVRL3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. PVRL3 plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.293917
HGNC ID: HGNC:17664