human PTPRN Over-expression AAV

Cat. No: AAV-220354

Availability: 3-5 weeks

Name: AAV-h-PTPRN

This is an AAV expressing Human PTPRN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PTPRN
Gene Name: protein tyrosine phosphatase, receptor type N
Gene ID: 5798
Gene Synonyms: IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N
ORF Size: 2853 bp
RefSeq#: BC070053
Gene Description: PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.89655
HGNC ID: HGNC:9676