human PLA2G5 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-219078
Availability:
Immediate
Name:
AAV-h-PLA2G5
This is an AAV expressing Human PLA2G5.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PLA2G5
- Gene Name
- phospholipase A2 group V
- Gene ID
- 5322
- Gene Synonyms
- FRFB; GV-PLA2; hVPLA(2); PLA2-10
- ORF Size
- 417 bp
- RefSeq#
- BC036792
- Gene Description
- PLA2G5 is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined.
- UniGene ID
- Hs.319438
- HGNC ID
- HGNC:9038
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