human PCNA Over-expression AAV

Cat. No: AAV-218393

Availability: 3-5 weeks

Name: AAV-h-PCNA

This is an AAV expressing Human PCNA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PCNA
Gene Name: proliferating cell nuclear antigen
Gene ID: 5111
Gene Synonyms: ATLD2
ORF Size: 786 bp
RefSeq#: BC000491
Gene Description: PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
UniGene ID: Hs.147433
HGNC ID: HGNC:8729