human MTHFR Over-expression AAV

Cat. No: AAV-215996

Availability: 3-5 weeks

Name: AAV-h-MTHFR

This is an AAV expressing Human MTHFR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MTHFR
Gene Name: methylenetetrahydrofolate reductase
Gene ID: 4524
ORF Size: 1971 bp
RefSeq#: BC053509
Gene Description: MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
UniGene ID: Hs.214142
HGNC ID: HGNC:7436