human KCND3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-212679
Availability:
Immediate
Name:
AAV-h-KCND3
This is an AAV expressing Human KCND3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- KCND3
- Gene Name
- potassium voltage-gated channel subfamily D member 3
- Gene ID
- 3752
- Gene Synonyms
- BRGDA9; KCND3L; KCND3S; KSHIVB; KV4.3; SCA19; SCA22
- ORF Size
- 1911 bp
- RefSeq#
- BC113477
- Gene Description
- Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
- UniGene ID
- Hs.666367
- HGNC ID
- HGNC:6239
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