human HS2ST1 Over-expression AAV

Cat. No: AAV-211533

Availability: 3-5 weeks

Name: AAV-h-HS2ST1

This is an AAV expressing Human HS2ST1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HS2ST1
Gene Name: heparan sulfate 2-O-sulfotransferase 1
Gene ID: 9653
Gene Synonyms: dJ604K5.2
ORF Size: 690 bp
RefSeq#: BC025384
Gene Description: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.
UniGene ID: Hs.48823
HGNC ID: HGNC:5193