human GLRA1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209991
Availability:
3-5 weeks
Name:
AAV-h-GLRA1
This is an AAV expressing Human GLRA1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GLRA1
- Gene Name
- glycine receptor alpha 1
- Gene ID
- 2741
- Gene Synonyms
- HKPX1; STHE
- ORF Size
- 1374 bp
- RefSeq#
- BC114947
- Gene Description
- GLRA1 is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.121490
- HGNC ID
- HGNC:4326
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