human GJB3 Over-expression AAV

Cat. No: AAV-209925

Availability: 3-5 weeks

Name: AAV-h-GJB3

This is an AAV expressing Human GJB3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GJB3
Gene Name: gap junction protein beta 3
Gene ID: 2707
Gene Synonyms: CX31; DFNA2; DFNA2B; EKV
ORF Size: 813 bp
RefSeq#: BC110640
Gene Description: GJB3 is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
UniGene ID: Hs.522561
HGNC ID: HGNC:4285