human GCHFR Over-expression AAV

Cat. No: AAV-209740

Availability: 3-5 weeks

Name: AAV-h-GCHFR

This is an AAV expressing Human GCHFR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GCHFR
Gene Name: GTP cyclohydrolase I feedback regulator
Gene ID: 2644
Gene Synonyms: GFRP; HsT16933; P35
ORF Size: 222 bp
RefSeq#: BC143904
Gene Description: GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
UniGene ID: Hs.631717
HGNC ID: HGNC:4194