human GABRB3 Over-expression AAV

Cat. No: AAV-209520

Availability: 3-5 weeks

Name: AAV-h-GABRB3

This is an AAV expressing Human GABRB3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GABRB3
Gene Name: gamma-aminobutyric acid type A receptor beta3 subunit
Gene ID: 2562
Gene Synonyms: ECA5; EIEE43
ORF Size: 1422 bp
RefSeq#: BC010641
Gene Description: GABRB3 encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. GABRB3 is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
UniGene ID: Hs.657298
HGNC ID: HGNC:4083