human FXN Over-expression AAV

Cat. No: AAV-209435

Availability: 3-5 weeks

Name: AAV-h-FXN

This is an AAV expressing Human FXN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FXN
Gene Name: frataxin
Gene ID: 2395
Gene Synonyms: CyaY; FA; FARR; FRDA; X25
ORF Size: 633 bp
RefSeq#: BC023633
Gene Description: This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.29978
HGNC ID: HGNC:3951