human FTCD Over-expression AAV

Name
AAV-h-FTCD

Cat No
AAV-209355

Availability
4-5 weeks

This is an AAV expressing Human FTCD.

AAV-209355

AAV-h-FTCD

Ready-to-use AAV expressing Human FTCD (formimidoyltransferase cyclodeaminase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LCHC1

Description (Vector)

FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.

Gene ID

10841

Gene Name (Vector)

formimidoyltransferase cyclodeaminase

Gene Symbol

FTCD

HGNC ID

HGNC:3974

ORF Size (aa)

1626

ORF Size (bp)

1626 bp

RefSeq ID

NM_006657

RefSeq Synonyms

NM_206965, NM_006657, NM_001320412, BC136395, BC136383, BC052248,

Species

human

UniGene ID

Hs.415846

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.