human FLVCR2 Over-expression AAV

Cat. No: AAV-209170

Availability: 3-5 weeks

Name: AAV-h-FLVCR2

This is an AAV expressing Human FLVCR2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FLVCR2
Gene Name: feline leukemia virus subgroup C cellular receptor family member 2
Gene ID: 55640
Gene Synonyms: C14orf58; CCT; EPV; FLVCRL14q; MFSD7C; PVHH
ORF Size: 1581 bp
RefSeq#: BC019087
Gene Description: FLVCR2 encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.615289
HGNC ID: HGNC:20105