human FARS2 Over-expression AAV

Name
AAV-h-FARS2

Cat No
AAV-208716

Availability
4-5 weeks

This is an AAV expressing Human FARS2.

AAV-208716

AAV-h-FARS2

Ready-to-use AAV expressing Human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

COXPD14; FARS1; HSPC320; PheRS; SPG77

Description (Vector)

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.

Gene ID

10667

Gene Name (Vector)

phenylalanyl-tRNA synthetase 2, mitochondrial

Gene Symbol

FARS2

HGNC ID

HGNC:21062

ORF Size (aa)

1356

ORF Size (bp)

1356 bp

RefSeq ID

NM_006567

RefSeq Synonyms

NM_006567, NM_001318872, BC021112, BC020239,

Species

human

UniGene ID

Hs.484547

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.