human DGKG Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-206923
Availability:
3-5 weeks
Name:
AAV-h-DGKG
This is an AAV expressing Human DGKG.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DGKG
- Gene Name
- diacylglycerol kinase gamma
- Gene ID
- 1608
- Gene Synonyms
- DAGK3; DGK-GAMMA
- ORF Size
- 2301 bp
- RefSeq#
- BC089411
- Gene Description
- DGKG encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.683449
- HGNC ID
- HGNC:2853
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