human DFNB59 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-206904
Availability:
3-5 weeks
Name:
AAV-h-DFNB59
This is an AAV expressing Human DFNB59.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DFNB59
- Gene Name
- deafness, autosomal recessive 59
- Gene ID
- 494513
- Gene Synonyms
- PJVK
- ORF Size
- 582 bp
- RefSeq#
- BC127903
- Gene Description
- DFNB59 is a member of the gasdermin family, a family which is found only in vertebrates. The encoded protein is required for the proper function of auditory pathway neurons. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59).
- UniGene ID
- Hs.87734
- HGNC ID
- HGNC:29502
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