human CTSK Over-expression AAV

Cat. No: AAV-206273

Availability: 3-5 weeks

Name: AAV-h-CTSK

This is an AAV expressing Human CTSK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CTSK
Gene Name: cathepsin K
Gene ID: 1513
Gene Synonyms: CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD
ORF Size: 990 bp
RefSeq#: BC016058
Gene Description: CTSK is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
UniGene ID: Hs.632466
HGNC ID: HGNC:2536