human ATIC Over-expression AAV

Cat. No: AAV-201651

Availability: 3-5 weeks

Name: AAV-h-ATIC

This is an AAV expressing Human ATIC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATIC
Gene Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene ID: 471
Gene Synonyms: AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH
ORF Size: 1779 bp
RefSeq#: BC008879
Gene Description: ATIC encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
UniGene ID: Hs.90280
HGNC ID: HGNC:794