human ASAH1 Over-expression AAV

Cat. No: AAV-201505

Availability: 3-5 weeks

Name: AAV-h-ASAH1

This is an AAV expressing Human ASAH1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ASAH1
Gene Name: N-acylsphingosine amidohydrolase 1
Gene ID: 427
Gene Synonyms: AC; ACDase; ASAH; PHP; PHP32; SMAPME
ORF Size: 1188 bp
RefSeq#: BC016481
Gene Description: ASAH1 encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
UniGene ID: Hs.633993
HGNC ID: HGNC:735