rat NPAP60 Over-expression AAV

Cat. No: AAV-294609

Availability: 3-5 weeks

Name: AAV-r-NPAP60

This is an AAV expressing Rat Nup50.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Nup50
Gene Name: nucleoporin 50
Gene ID: 25497
Gene Synonyms: Npap60; Rtp60
ORF Size: 1404 bp
RefSeq#: BC097337
Gene Description: Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.