mouse GUCA1A shRNA silencing AAV

Cat. No: shAAV-260925

Availability: 6-8 weeks

Name: AAV-m-GUCA1A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Guca1a.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Guca1a
Gene Name: guanylate cyclase activator 1a (retina)
Gene ID: 14913
Gene Synonyms: GC-A; Gcap1; Guca1; mGCAP1
ORF Size: 609 bp
RefSeq#: NM_008189
Gene Description: Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
UniGene ID: Mm.16224