mouse CYBB shRNA silencing AAV

Cat. No: shAAV-256443

Availability: 6-8 weeks

Name: AAV-m-CYBB-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cybb.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cybb
Gene Name: cytochrome b-245, beta polypeptide
Gene ID: 13058
Gene Synonyms: C88302; Cgd; CGD91-phox; Cyd; gp91-1; gp91phox; Nox2
ORF Size: 1713 bp
RefSeq#: NM_007807
Gene Description: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
UniGene ID: Mm.200362