human EPHB4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-207996
Availability:
4-5 weeks
Name:
AAV-h-EPHB4-shRNA
This is an AAV expressing shRNA for silencing of Human EPHB4.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- EPHB4
- Gene Name
- EPH receptor B4
- Gene ID
- 2050
- Gene Synonyms
- HTK; MYK1; TYRO11
- ORF Size
- 2964 bp
- RefSeq#
- NM_004444
- Gene Description
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
- UniGene ID
- Hs.437008
- HGNC ID
- HGNC:3395
Related Products
Product | Cat No. |
---|---|
AAV-h-EPHB4 | AAV-207996 |
AAV-m-EPHB4 | AAV-258582 |
Ad-h-EPHB4 | ADV-207996 |
Ad-m-EPHB4 | ADV-258582 |
AAV-m-EPHB4-shRNA | shAAV-258582 |
Ad-h-EPHB4-shRNA | shADV-207996 |
Ad-m-EPHB4-shRNA | shADV-258582 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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