human IL20 shRNA silencing AAV

Cat. No: shAAV-212124

Availability: 6-8 weeks

Name: AAV-h-IL20-shRNA

This is an AAV expressing shRNA for silencing of Human IL20.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IL20
Gene Name: interleukin 20
Gene ID: 50604
Gene Synonyms: IL-20; IL10D; ZCYTO10
ORF Size: 531 bp
RefSeq#: NM_018724
Gene Description: IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
UniGene ID: Hs.272373
HGNC ID: HGNC:6002