human SGCZ shRNA silencing AAV

Cat. No: shAAV-222847

Availability: 6-8 weeks

Name: AAV-h-SGCZ-shRNA

This is an AAV expressing shRNA for silencing of Human SGCZ.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SGCZ
Gene Name: sarcoglycan zeta
Gene ID: 137868
Gene Synonyms: ZSG1
ORF Size: 798 bp
RefSeq#: NM_139167
Gene Description: The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
UniGene ID: Hs.676196
HGNC ID: HGNC:14075