human PSCA shRNA silencing AAV

Cat. No: shAAV-214165

Availability: 6-8 weeks

Name: AAV-h-PSCA-shRNA

This is an AAV expressing shRNA for silencing of Human PSCA.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PSCA
Gene Name: prostate stem cell antigen
Gene ID: 8000
Gene Synonyms: PRO232
ORF Size: 372 bp
RefSeq#: NM_005672
Gene Description: PSCA encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. PSCA is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. PSCA includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.711174
HGNC ID: HGNC:9500