mouse LDLR shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-263355
Availability:
Immediate
Name:
AAV-m-LDLR-shRNA
This is an AAV expressing shRNA for silencing of Mouse Ldlr.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ldlr
- Gene Name
- low density lipoprotein receptor
- Gene ID
- 16835
- Gene Synonyms
- Hlb301
- ORF Size
- 2589 bp
- RefSeq#
- NM_010700
- Gene Description
- Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
- UniGene ID
- Mm.3213
Related Products
Product | Cat No. |
---|---|
AAV-h-LDLR | AAV-213796 |
AAV-m-LDLR | AAV-263355 |
Ad-h-LDLR | ADV-213796 |
Ad-m-LDLR | ADV-263355 |
AAV-h-LDLR-shRNA | shAAV-213796 |
Ad-h-LDLR-shRNA | shADV-213796 |
Ad-m-LDLR-shRNA | shADV-263355 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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