mouse NCOA3 shRNA silencing AAV

Cat. No: shAAV-280906

Availability: 6-8 weeks

Name: AAV-m-NCOA3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ncoa3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ncoa3
Gene Name: nuclear receptor coactivator 3
Gene ID: 17979
Gene Synonyms: 2010305B15Rik; Actr; Aib1; AW321064; bHLHe42; KAT13B; p/Cip; pCip; Rac3; Src3; Tram-1; Tram1
ORF Size: 4212 bp
RefSeq#: NM_008679
Gene Description: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. Interacts with PSMB9.
UniGene ID: Mm.476883