human F2RL3 shRNA silencing AAV

Cat. No: shAAV-208228

Availability: 6-8 weeks

Name: AAV-h-F2RL3-shRNA

This is an AAV expressing shRNA for silencing of Human F2RL3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: F2RL3
Gene Name: F2R like thrombin/trypsin receptor 3
Gene ID: 9002
Gene Synonyms: PAR4
ORF Size: 1158 bp
RefSeq#: NM_003950
Gene Description: Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
UniGene ID: Hs.137574
HGNC ID: HGNC:3540