human HABP2 shRNA silencing AAV

Cat. No: shAAV-210756

Availability: 6-8 weeks

Name: AAV-h-HABP2-shRNA

This is an AAV expressing shRNA for silencing of Human HABP2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HABP2
Gene Name: hyaluronan binding protein 2
Gene ID: 3026
Gene Synonyms: FSAP; HABP; HGFAL; NMTC5; PHBP
ORF Size: 1683 bp
RefSeq#: NM_004132
Gene Description: HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.422542
HGNC ID: HGNC:4798