human PHLDA2 shRNA silencing AAV

Cat. No: shAAV-218844

Availability: 6-8 weeks

Name: AAV-h-PHLDA2-shRNA

This is an AAV expressing shRNA for silencing of Human PHLDA2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PHLDA2
Gene Name: pleckstrin homology like domain family A member 2
Gene ID: 7262
Gene Synonyms: BRW1C; BWR1C; HLDA2; IPL; TSSC3
ORF Size: 459 bp
RefSeq#: NM_003311
Gene Description: PHLDA2 is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. PHLDA2 has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
UniGene ID: Hs.154036
HGNC ID: HGNC:12385