human NAT2 shRNA silencing AAV

Cat. No: shAAV-216343

Availability: 6-8 weeks

Name: AAV-h-NAT2-shRNA

This is an AAV expressing shRNA for silencing of Human NAT2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NAT2
Gene Name: N-acetyltransferase 2
Gene ID: 10
Gene Synonyms: AAC2; NAT-2; PNAT
ORF Size: 873 bp
RefSeq#: NM_000015
Gene Description: NAT2 encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2).
UniGene ID: Hs.2
HGNC ID: HGNC:7646