human TDGF1 shRNA silencing AAV

Cat. No: shAAV-225261

Availability: 6-8 weeks

Name: AAV-h-TDGF1-shRNA

This is an AAV expressing shRNA for silencing of Human TDGF1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TDGF1
Gene Name: teratocarcinoma-derived growth factor 1
Gene ID: 6997
Gene Synonyms: CR; CRGF; CRIPTO
ORF Size: 567 bp
RefSeq#: NM_003212
Gene Description: TDGF1 encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.385870
HGNC ID: HGNC:11701