mouse HAMP shRNA silencing AAV

Cat. No: shAAV-261095

Availability: 6-8 weeks

Name: AAV-m-HAMP-shRNA

This is an AAV expressing shRNA for silencing of Mouse Hamp.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hamp
Gene Name: hepcidin antimicrobial peptide
Gene ID: 84506
Gene Synonyms: Hamp1; Hepc; Hepc1
ORF Size: 252 bp
RefSeq#: NM_032541
Gene Description: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages (By similarity)|Function: Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
UniGene ID: Mm.439939