mouse SCN10A shRNA silencing AAV

Cat. No: shAAV-271442

Availability: 6-8 weeks

Name: AAV-m-SCN10A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Scn10a.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Scn10a
Gene Name: sodium channel, voltage-gated, type X, alpha
Gene ID: 20264
Gene Synonyms: Nav1.8; PN3; SNS
ORF Size: 5871 bp
RefSeq#: NM_009134
Gene Description: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of the associated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms (By similarity).
UniGene ID: Mm.247042