human TBX19 shRNA silencing AAV

Cat. No: shAAV-225154

Availability: 4-5 weeks

Name: AAV-h-TBX19-shRNA

This is an AAV expressing shRNA for silencing of Human TBX19.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TBX19
Gene Name: T-box 19
Gene ID: 9095
Gene Synonyms: dJ747L4.1; TBS19; TPIT
ORF Size: 1347 bp
RefSeq#: NM_005149
Gene Description: TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
UniGene ID: Hs.716656
HGNC ID: HGNC:11596