human TBX19 shRNA silencing Adenovirus

Name
Ad-h-TBX19-shRNA

Cat No
shADV-225154

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TBX19.

shADV-225154

Ad-h-TBX19-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBX19 (T-box 19). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

dJ747L4.1; TBS19; TPIT

Description (Vector)

TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.

Gene ID

9095

Gene Name (Vector)

T-box 19

Gene Symbol

TBX19

HGNC ID

HGNC:11596

ORF Size (aa)

1347

ORF Size (bp)

1347 bp

RefSeq ID

NM_005149

RefSeq Synonyms

NM_005149, BC093666, BC093664,

Species

human

UniGene ID

Hs.716656

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.