human ASNA1 shRNA silencing AAV

Cat. No: shAAV-201566

Availability: 4-5 weeks

Name: AAV-h-ASNA1-shRNA

This is an AAV expressing shRNA for silencing of Human ASNA1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ASNA1
Gene Name: arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Gene ID: 439
Gene Synonyms: ARSA-I; ARSA1; ASNA-I; GET3; TRC40
ORF Size: 1047 bp
RefSeq#: NM_004317
Gene Description: ASNA1 represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
UniGene ID: Hs.465985
HGNC ID: HGNC:752