human APOC3 shRNA silencing AAV

Cat. No: shAAV-201194

Availability: 6-8 weeks

Name: AAV-h-APOC3-shRNA

This is an AAV expressing shRNA for silencing of Human APOC3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: APOC3
Gene Name: apolipoprotein C3
Gene ID: 345
Gene Synonyms: APOCIII; HALP2
ORF Size: 300 bp
RefSeq#: NM_000040
Gene Description: Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
UniGene ID: Hs.73849
HGNC ID: HGNC:610