mouse LEPR shRNA silencing AAV

Cat. No: shAAV-263380

Availability: 6-8 weeks

Name: AAV-m-LEPR-shRNA

This is an AAV expressing shRNA for silencing of Mouse Lepr.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Lepr
Gene Name: leptin receptor
Gene ID: 16847
Gene Synonyms: db; diabetes; Leprb; LEPROT; Modb1; OB-RGRP; obese-like; obl; Obr
ORF Size: 2457 bp
RefSeq#: NM_010704
Gene Description: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
UniGene ID: Mm.259282