mouse LEPR Over-expression AAV

Name 
AAV-m-LEPR
Cat No 
AAV-263380
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lepr.

AAV-263380
AAV-m-LEPR

Ready-to-use AAV expressing Mouse Lepr (leptin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
db; diabetes; Leprb; LEPROT; Modb1; OB-RGRP; obese-like; obl; Obr
Description (Vector)
Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
Gene ID
16847
Gene Name (Vector)
leptin receptor
Gene Symbol
Lepr
ORF Size (aa)
2457
ORF Size (bp)
2457 bp
RefSeq ID
NM_010704
RefSeq Synonyms
NM_146146, NM_010704, NM_001122899, BC082551,
Species
mouse
UniGene ID
Mm.259282

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.