human CYP4F12 shRNA silencing AAV

Cat. No: shAAV-206513

Availability: 6-8 weeks

Name: AAV-h-CYP4F12-shRNA

This is an AAV expressing shRNA for silencing of Human CYP4F12.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CYP4F12
Gene Name: cytochrome P450 family 4 subfamily F member 12
Gene ID: 66002
Gene Synonyms: CYPIVF12; F22329_1
ORF Size: 1575 bp
RefSeq#: NM_023944
Gene Description: CYP4F12 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. CYP4F12 is part of a cluster of cytochrome P450 genes on chromosome 19.
UniGene ID: Hs.591000
HGNC ID: HGNC:18857