human SOAT2 shRNA silencing AAV

Cat. No: shAAV-223969

Availability: 6-8 weeks

Name: AAV-h-SOAT2-shRNA

This is an AAV expressing shRNA for silencing of Human SOAT2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SOAT2
Gene Name: sterol O-acyltransferase 2
Gene ID: 8435
Gene Synonyms: ACACT2; ACAT2; ARGP2
ORF Size: 1569 bp
RefSeq#: NM_003578
Gene Description: Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
UniGene ID: Hs.656544
HGNC ID: HGNC:11178