human SOX2 shRNA silencing AAV

Cat. No: shAAV-224023

Availability: 4-5 weeks

Name: AAV-h-SOX2-shRNA

This is an AAV expressing shRNA for silencing of Human SOX2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SOX2
Gene Name: SRY-box 2
Gene ID: 6657
Gene Synonyms: ANOP3; MCOPS3
ORF Size: 954 bp
RefSeq#: NM_003106
Gene Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
UniGene ID: Hs.518438
HGNC ID: HGNC:11195