human IGSF8 shRNA silencing AAV

Cat. No: shAAV-212001

Availability: 6-8 weeks

Name: AAV-h-IGSF8-shRNA

This is an AAV expressing shRNA for silencing of Human IGSF8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IGSF8
Gene Name: immunoglobulin superfamily member 8
Gene ID: 93185
Gene Synonyms: CD316; CD81P3; EWI-2; EWI2; KCT-4; LIR-D1; PGRL
ORF Size: 1842 bp
RefSeq#: NM_052868
Gene Description: IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
UniGene ID: Hs.332012
HGNC ID: HGNC:17813