human PPM1E shRNA silencing AAV

Cat. No: shAAV-219578

Availability: 4-5 weeks

Name: AAV-h-PPM1E-shRNA

This is an AAV expressing shRNA for silencing of Human PPM1E.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PPM1E
Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1E
Gene ID: 22843
Gene Synonyms: caMKN; CaMKP-N; POPX1; PP2CH
ORF Size: 2274 bp
RefSeq#: NM_014906
Gene Description: PPM1E encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.
UniGene ID: Hs.245044
HGNC ID: HGNC:19322