human PPM1E Over-expression AAV

Name 
AAV-h-PPM1E
Cat No 
AAV-219578
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PPM1E.

AAV-219578
AAV-h-PPM1E

Ready-to-use AAV expressing Human PPM1E (protein phosphatase, Mg2+/Mn2+ dependent 1E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
caMKN; CaMKP-N; POPX1; PP2CH
Description (Vector)
PPM1E encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
22843
Gene Name (Vector)
protein phosphatase, Mg2+/Mn2+ dependent 1E
Gene Symbol
PPM1E
HGNC ID
HGNC:19322
ORF Size (aa)
2274
ORF Size (bp)
2274 bp
RefSeq ID
NM_014906
RefSeq Synonyms
NM_014906, BC151228, BC136290,
Species
human
UniGene ID
Hs.245044

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.