mouse ECSIT shRNA silencing AAV

Cat. No: shAAV-257735

Availability: 6-8 weeks

Name: AAV-m-ECSIT-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ecsit.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ecsit
Gene Name: ECSIT signalling integrator
Gene ID: 26940
Gene Synonyms: Sitpec
ORF Size: 1308 bp
RefSeq#: NM_012029
Gene Description: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
UniGene ID: Mm.425568